论文部分内容阅读
目的:分析碳酸锂与丙基硫氧嘧啶对Graves病重型甲亢的临床疗效。方法:将68例Graves病重型甲亢患者按照治疗方式的不同分为A、B两组各34例,A组经碳酸锂治疗,B组经丙基硫氧嘧啶治疗,对比两组患者治疗效果。结果:A组患者临床治愈率79.4%明显高于B组患者临床治愈率41.2%,甲状腺激素水平低于B组,P<0.05;两组早发甲状腺功能减退发生率对比,P>0.05。结论:碳酸锂与丙基硫氧嘧啶均可有效治疗Graves病重型甲亢,碳酸锂治疗效果优于丙基硫氧嘧啶。
Objective: To analyze the clinical effect of lithium carbonate and propylthiouracil on severe hyperthyroidism with Graves disease. Methods: Sixty-six patients with Graves’ disease of severe hyperthyroidism were divided into two groups (A and B), 34 cases in each group. A group was treated with lithium carbonate and B group was treated with propylthiouracil. The therapeutic effect was compared between the two groups. Results: The cure rate of group A was 79.4%, which was significantly higher than that of group B (41.2%). The thyroid hormone level was lower than that of group B (P <0.05). The incidence of premature thyroid hypothyroidism in both groups was significantly lower than that of group B (P> 0.05). CONCLUSION: Both lithium carbonate and propylthiouracil are effective in treating Graves’ disease with hyperthyroidism. Lithium carbonate is better than propylthiouracil in treatment of severe hyperthyroidism.