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目的:探讨孕期细菌性及非细菌感染与胎膜早破的关系。方法:通过对2012年7月-2013年7月在笔者所在医院进行治疗的60例胎膜早破的产妇为试验组,随机选取同期在笔者所在医院进行住院待产60例正常产妇为对照组。对两组产妇的宫颈和阴道分泌物进行宫颈支原体(UU)、细菌性阴道病(BV)、假丝酵母菌(VVC)、衣原体(CT)及羊膜病检测,同时比较两组产妇的妊娠结局及产后感染情况。结果:试验组产妇的UU、BV、VVC及CT生殖道感染的比例较对照组产妇高,差异有统计学意义(P<0.05);试验组产妇的绒毛膜羊膜炎及产妇产后感染率较对照组高,差异有统计学意义(P<0.05);试验组新生儿出现死亡、早产、窒息数较对照组新生儿多,差异有统计学意义(P<0.05)。结论:胎膜早破同UU、CT、BV、VVC、羊膜病密切相关,需要对妊娠早、中期产妇进行筛查,采取相应的预防措施,降低胎膜早破的发生,避免给产妇和新生儿造成不良影响。孕期细菌性和非细菌性感染的诊断对胎膜早破具有十分重要的意义,临床值得推广。
Objective: To investigate the relationship between bacterial and non-bacterial infection during pregnancy and premature rupture of membranes. Methods: From July 2012 to July 2013, 60 cases of premature rupture of membranes in the author’s hospital were selected as the experimental group and 60 normal maternal inpatients were randomly selected as the control group in the same hospital at the same time. Cervical and vaginal secretions from two groups of women were tested for cervical mycoplasma (UU), bacterial vaginosis (BV), candida (VVC), chlamydia (CT) and amniotic membrane disease. Pregnancy outcomes of the two groups were compared And postpartum infection. Results: The proportion of UU, BV, VVC and CT genital infection in the experimental group was higher than that in the control group (P <0.05). The chorioamnionitis and the postpartum infection rate in the experimental group were more than those in the control group The difference was statistically significant (P <0.05). There were more newborns in the experimental group than in the control group (P <0.05). Conclusion: Premature rupture of membranes is closely related to UU, CT, BV, VVC and amniotic membrane disease. It is necessary to screen the pregnant women in the first trimester and the middle one to take appropriate preventive measures to reduce the occurrence of premature rupture of membranes, Children have an adverse effect. The diagnosis of bacterial and non-bacterial infections during pregnancy is of great significance to the premature rupture of membranes and should be clinically worthy of promotion.