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目的了解育龄妇女泌尿生殖道解脲支原体(Uu)、人型支原体(Mh)感染及药物敏感情况,为临床合理用药和有效控制感染提供依据。方法采用支原体(Uu/Mh)分离培养药敏试剂盒(微生物检验法),对泌尿生殖道感染患者分泌物进行支原体培养及药敏试验。结果 2 836例标本中支原体培养阳性1 492例,阳性率为52.6%,其中单纯Uu阳性率为39.0%;单纯Mh阳性率为2.4%;Uu合并Mh混合感染阳性率为11.2%。支原体感染好发于26岁~35岁育龄妇女,并且白带清洁度异常者阳性率明显高于白带清洁度正常者,差异有统计学意义(P<0.05)。药敏结果表明,支原体对交沙霉素、强力霉素和美满霉素敏感度较高。结论女性泌尿生殖道支原体的感染率较高,以Uu为主,支原体多数具有多重耐药性,临床需根据药敏结果选择有效药物,减少耐药菌株的产生。
Objective To understand genitourinary Uu, Mh infection and drug susceptibility in women of childbearing age and provide evidences for rational drug use and effective infection control. Methods Mycoplasma (Uu / Mh) isolation and culture kit was used to detect mycoplasma secretion and drug susceptibility test in patients with genitourinary tract infection. Results A total of 1 492 mycoplasma were positive in 2 836 specimens, the positive rate was 52.6%. The positive rate of pure Uu was 39.0%. The positive rate of pure Mh was 2.4%. The positive rate of Uu combined with Mh was 11.2%. Mycoplasma infection occurs in women of childbearing age 26 ~ 35 years old, and the positive rate of abnormal vaginal cleanliness was significantly higher than that of normal vaginal discharge, the difference was statistically significant (P <0.05). Susceptibility results showed that Mycoplasma josamycin, doxycycline and minocycline susceptibility higher. Conclusions The prevalence of mycoplasmas in female genitourinary tract is high, mainly Uu. Most of mycoplasma have multi-drug resistance. In clinical practice, effective drugs should be selected according to drug susceptibility results to reduce the generation of drug-resistant strains.