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将稳定转染了大鼠酪氨酶羟化酶（Ｔｙｒｏｓｉｎｅｈｙｄｒｏｘｙｌａｓｅ，ＴＨ）基因的大鼠成肌细胞移植于帕金森病大鼠模型的纹状体，进行基因治疗研究。ＲＴ－ＰＣＲ和免疫组织化学检测都证明转基因细胞可在纹状体内存活并表达ＴＨ，动物的不对称旋转行为明显改善，而且疗效可维持半年以上。
Rat myoblasts stably transfected with rat tyrosinase hydroxylase (TH) gene were transplanted into the striatum of a rat model of Parkinson’s disease for gene therapy research. Both RT-PCR and immunohistochemistry proved that the transgenic cells could survive and express TH in the striatum. The asymmetric rotation behavior of the animals was significantly improved, and the effect could be maintained for more than six months.