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目的探讨脑梗死患者血同型半胱氨酸、血尿酸、血纤维蛋白原、血糖、血脂水平的变化及其临床意义。方法检测62例脑梗死患者(A组)的血同型半胱氨酸(Hcy)、血尿酸(UA)、血纤维蛋白原(FIB)、血糖(GLU)以及6项血脂指标,并与对照组(B组)39例的检测结果进行比较。结果脑梗死患者的血Hcy、UA、FIB、GLU、胆固醇(TC)、甘油三酯(TG)含量均高于对照组(P<0.001～P<0.05),高密度脂蛋白(HDL)、载脂蛋白A1(ApoA1)含量均低于对照组(P<0.005～P<0.05),低密度脂蛋白(LDL)、载脂蛋白B(ApoB)含量变化差异均无统计学意义(P>0.05)。结论血Hcy、UA、FIB、GLU、TC、TG的水平升高,HDL、ApoA1的水平下降与脑梗死均有一定关系,应重视对高同型半胱氨酸、高尿酸、高纤维蛋白原、高血糖、高血脂的积极防治。
Objective To investigate the changes of plasma homocysteine, serum uric acid, fibrinogen, blood glucose, blood lipids and their clinical significance in patients with cerebral infarction. Methods The blood homocysteine (Hcy), serum uric acid (UA), fibrinogen (FIB), blood glucose (GLU) and blood lipid levels were measured in 62 patients with cerebral infarction (A group) (Group B) 39 cases of the test results were compared. Results The contents of Hcy, UA, FIB, GLU, TC and TG in the patients with cerebral infarction were significantly higher than those in the control group (P <0.001 and P < The contents of ApoA1 and ApoA1 were lower than those in the control group (P <0.005 ~ P <0.05), but there was no significant difference in the contents of LDL and ApoB (P> 0.05) . Conclusions The levels of Hcy, UA, FIB, GLU, TC, TG in blood are elevated, and the levels of HDL and ApoA1 are related to cerebral infarction. High homocysteine, high uric acid, high fibrinogen, High blood sugar, high blood lipids prevention and treatment.