胃粘膜存在与肺内相似的表面活性磷脂。它由粘液细胞分泌,增加粘液层的粘滞性,使胃粘膜表面具疏水性,从而参与屏障作用。外源性表面活性磷脂同样具胃粘膜保护作用。阿斯匹林、胆盐等对胃粘膜的损伤作用,均与其破坏粘膜表面疏水性有关;前列腺素的胃上皮保护作用,部分也是通过增加内源性表面活性磷脂完成的。 Gastric mucosa exists in the lung similar to the surface-active phospholipids. It is secreted by mucus cells, increasing the viscosity of the mucus layer, making the gastric mucosal surface hydrophobic, thus participating in the barrier function. Exogenous surface active phospholipids with the same protective effect of gastric mucosa. Aspirin, bile salts and other damage to the gastric mucosa, are related to its destruction of mucosal surface hydrophobicity; prostaglandin protective effect of the stomach’s epithelium, partly through the addition of endogenous surfactant phospholipid to complete.