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目的探讨本地区男性慢性前列腺炎感染真菌的分布规律及耐药性,为临床合理使用抗真菌药物提供依据。方法对临床慢性前列腺炎患者前列腺液真菌培养分离的菌株鉴定,用API-AUX20C真菌ID条板或RyidNicroscan真菌ID条板进行鉴定分型,纸片扩散法进行药敏试验。结果158株真菌中,白色念珠菌感染率高,占46·2%,热带念珠菌占30·4%,光滑念珠菌占13·3%,对5-氟胞嘧啶、氟康唑和咪康唑的耐药率很高,分别是22·2%、34·8%和25·3%。结论本地区慢性前列腺炎感染真菌分离率高,及时进行真菌的培养和药敏试验,对临床控制感染和合理使用抗真菌药物具有重要意义。
Objective To investigate the distribution and drug resistance of fungal infections in men with chronic prostatitis in this region and to provide basis for the clinical rational use of antifungal drugs. Methods The strains isolated from prostatic fluid fungal culture in patients with chronic prostatitis were identified and identified by API-AUX20C fungal ID strip or RyidNicroscan fungal ID strip. Susceptibility testing was performed by disk diffusion method. Results Among the 158 fungi, Candida albicans infection rate was 46.2%, Candida tropicalis was 30.4%, Candida glabrata was 13.3%, and 5-fluorocytosine, fluconazole and miconazole The rates of resistance to azole were high at 22.2%, 34.8% and 25.3%, respectively. Conclusion Chronic prostatitis infection fungal isolation in this area, timely fungal culture and drug susceptibility testing, clinical control of infection and the rational use of antifungal drugs is of great significance.