美国Physiologica公司于1994年创建的位于马塞诸塞州的Bion公司正计划开发一种与下丘脑抑制因子(HIF)有关的新的激素类药物,用于治疗充血性心力衰竭和高血压。 据认为,HIF能控制钠离子泵,被称为“哺乳类的洋地黄”(“a mammalian counterpart to digitalis”)。该物质首先由马塞诸塞州总医院Garner Haupert博士在牛的下丘 Bion, a Massachusetts-based company founded by Physiologica in the United States, is planning to develop a new hormone drug related to hypothalamic inhibitory factor (HIF) for the treatment of congestive heart failure and hypertension. It is believed that HIF can control the sodium ion pump and is called “a mammalian counterpart to digitalis”. The substance was first performed by Dr. Garner Haupert of the Massachusetts General Hospital in the cattle