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为了评价健脾补肾解毒法中药对猴艾滋病的干预效果。该实验选用8只同期SIV感染恒河猴,随机分为2组:健脾补肾解毒法中药组(以下简称中药组)和抗病毒药组,分别给予中药及抗病毒治疗8周,每4周采集外周血检测。结果显示,健脾补肾解毒法中药虽然不能像HAART一样明显降低血浆病毒载量,但可以升高外周血CD4,该亚群主要为CD4纯真细胞;使CD4和CD8功能细胞数量增加,增强对病原体的免疫应答;在一定程度上延缓了脾虚的出现和进展。表明该药有较好的免疫调节作用,具有相当的临床价值和应用前景。
In order to evaluate the effect of spleen and kidney detoxification method of Chinese AIDS on monkey AIDS. In this experiment, 8 synchronous SIV infected rhesus monkeys were randomly divided into 2 groups: Chinese medicine group (hereinafter referred to as Chinese medicine group) and Chinese antiviral group with Chinese medicine and antiviral treatment for 8 weeks and every 4 weeks Collect peripheral blood test. The results showed that although the traditional Chinese medicine of invigorating the spleen and invigorating the kidney and detoxifying method can not obviously reduce the plasma viral load like the HAART, it can raise the CD4 of the peripheral blood, which is mainly the CD4 pure cells; increase the numbers of the CD4 and CD8 functional cells, Immune response; to some extent, delayed the emergence and progress of spleen deficiency. Show that the drug has a better immunomodulatory effect, with considerable clinical value and application prospects.