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为了评价多巴酚丁胺负荷试验99mTc-MIBI心肌单光子发射型计算机断层(SPECT)显像检测冠心病的准确性,对比了21例(22例次)临床确诊或可疑冠心病患者的多巴酚丁胺负荷试验99mTc-MIBI心肌SPECT显像与冠状动脉造影的结果。有明显冠状动脉狭窄的12例患者,11例多巴酚丁胺99mTc-MIBI心肌SPECT异常;冠状动脉造影正常的7例患者,其中6例心肌SPECT正常。多巴酚丁胺99mTc-MIBI心肌SPECT检测冠心病的灵敏度为92%(11/12),特异性为86%(6/7)。初步表明,多巴酚丁胺药物负荷试验99mTc-MIBI心肌SPECT显像是安全的,对于检测冠状动脉病变有较高的灵敏度和特异性,具有较好的临床应用前景。
To evaluate the accuracy of dobutamine stress 99mTc-MIBI single photon emission computed tomography (SPECT) imaging in the detection of coronary heart disease, 21 patients (22 episodes) with clinically diagnosed or suspected coronary artery disease Phenobutylamine stress test 99mTc-MIBI myocardial SPECT imaging and coronary angiography results. There were 12 patients with obvious coronary artery stenosis and 11 patients with dobutamine 99mTc-MIBI myocardial SPECT abnormality. Seven patients with normal coronary angiography, of which 6 had normal myocardial SPECT. Dobutamine 99mTc-MIBI myocardial SPECT detection of coronary heart disease was 92% (11/12) with a specificity of 86% (6/7). The preliminary results showed that the dobutamine stress test 99mTc-MIBI myocardial SPECT imaging is safe and has high sensitivity and specificity for the detection of coronary artery disease, and has a good clinical application prospect.