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目的探讨伴有炎症表现的视网膜母细胞瘤(Rb)的误诊原因与鉴别诊断。方法回顾性分析17例貌似眼部炎症Rb的临床及病理资料。结果病例最初都曾多次被误诊为感染性眼炎,当作炎症治疗。误诊的主要原因是这些病例具有较典型的炎症表现,而未怀疑肿瘤,最终经B超、CT和/或病理学检查确诊Rb。组织病理学检查发现绝大多数病例属眼外期,并伴有瘤组织坏死和炎性细胞浸润。结论儿童眼部炎症表现应考虑Rb的可能性,B超、CT和组织病理学检查有助于鉴别诊断
Objective To investigate the misdiagnosis and differential diagnosis of retinoblastoma (Rb) accompanied by inflammatory manifestations. Methods The clinical and pathological data of 17 cases with ocular inflammation Rb were retrospectively analyzed. Results The cases were initially misdiagnosed as infectious ophthalmia for many times, as an inflammation treatment. The main reason for misdiagnosis is that these cases have a more typical inflammatory manifestations without suspected neoplasia, and eventually diagnosed with Rb by ultrasonography, CT and / or pathology. Histopathological examination found that the vast majority of cases are outside the eye, accompanied by tumor necrosis and inflammatory cell infiltration. Conclusion The possibility of Rb should be considered in children with ocular inflammatory manifestations. B-ultrasound, CT and histopathological examination are helpful to the differential diagnosis