目的探讨哌拉西林钠他唑巴坦钠治疗老年呼吸道感染的临床疗效。方法 240例老年呼吸道感染患者,根据治疗方法不同分为对照组和观察组,各120例。对照组采用头孢哌酮钠舒巴坦钠治疗,观察组采用哌拉西林钠他唑巴坦钠治疗。比较两组临床疗效及患者细菌清除率。结果对照组治愈21例,显效45例,进步27例,无效27例,总有效率为77.5%;观察组治愈26例,显效49例,进步36例,无效9例,总有效率为92.5%;观察组总有效率高于对照组,差异有统计学意义(P<0.05)。对照组痰液培养出致病菌89株,73株细菌得到清除,细菌清除率为82.02%;观察组痰液培养出致病菌93株,78株细菌得到清除,细菌清除率为83.87%;两组细菌清除率比较,差异无统计学意义(P>0.05)。结论哌拉西林钠他唑巴坦钠治疗老年呼吸道感染的临床疗效确切,细菌清除率高,值得推广应用。 Objective To investigate the clinical efficacy of piperacillin-tazobactam sodium in the treatment of senile respiratory tract infection. Methods A total of 240 elderly patients with respiratory tract infection were divided into control group and observation group according to different treatment methods, 120 cases in each. The control group was treated with cefoperazone sodium and sulbactam sodium. The observation group was treated with piperacillin sodium and tazobactam sodium. The clinical efficacy and bacterial clearance of patients in both groups were compared. Results In the control group, 21 cases were cured, 45 cases markedly improved, 27 cases improved, 27 cases ineffective and the total effective rate was 77.5%. In the observation group, 26 cases were cured, 49 cases markedly improved, 36 cases improved and 9 ineffective. The total effective rate was 92.5% ; The total effective rate in observation group was higher than that in control group, the difference was statistically significant (P <0.05). In the control group, 89 strains of pathogens were cultured in the sputum, and 73 strains of bacteria were removed. The bacterial clearance rate was 82.02%. 93 strains of pathogens were cultured in the sputum of the observation group and 78 strains of bacteria were removed. The bacterial clearance rate was 83.87%. There was no significant difference in bacterial clearance between the two groups (P> 0.05). Conclusion Piperacillin sodium tazobactam sodium treatment of elderly patients with respiratory tract infection is clinically effective, high bacterial clearance, it is worth promoting the application.