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特发性血小板减少性紫癜(ITP)是临床上最常见的出血性疾病,婴幼儿较多见。其特点为血小板数目减少,骨髓巨核细胞发育及成熟障碍,表现为皮肤、黏膜、内脏的出血。ITP的发病机制目前尚未阐明,近年研究显示,病毒感染和接种疫苗等与ITP的发病存在联系。2013年8月,温州市瓯海区某预防接种门诊接种麻疹-风疹联合减毒活疫苗(简称麻-风疫苗)后发生ITP 1例,现将情况报道如下。
Idiopathic thrombocytopenic purpura (ITP) is the most common clinical bleeding disorder, infants and young children are more common. It is characterized by a reduction in the number of platelets, the development of bone marrow megakaryocytes and maturation disorders, manifested as skin, mucous membranes, visceral bleeding. The pathogenesis of ITP has not been elucidated yet. Studies in recent years show that there is a link between viral infection and vaccination and the pathogenesis of ITP. In August 2013, 1 case of ITP occurred after a vaccination clinic in Ouhai District of Wenzhou City was inoculated with measles-rubella combined attenuated live vaccine (hereinafter referred to as “Ma-wind vaccine”). The situation is reported as follows.