自身免疫病如系统性红斑狼疮(SLE)、类风湿关节炎(RA)、系统性硬化(SSc)等具有较高的致残率和致死率。这些疾病不仅造成患者本身的极大负担和伤害,而且使家庭和社会负担明显增加。因此,近十年来人们更趋于早期和更积极地给予治疗以防止或延缓患者内脏器官出现明显的不可逆损伤 Autoimmune diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis (SSc) have high morbidity and mortality. These diseases not only cause great burden and harm to the patients themselves, but also significantly increase the burden on families and society. Therefore, in the past ten years, people tend to be treated more early and more aggressively to prevent or delay obvious irreversible damage to internal organs of patients