一、SM↑转移试验给正常大鼠(10只)经气管内依次注入从染尘后16、33、67、90和130天的大鼠肺中制取的SM↑后,经2个月解剖。肺组织间质部分和肺泡腔内有大量巨噬细胞及多核大巨噬细胞,间有成纤维细胞和浆细胞的增生,肺泡间隔明显增宽。支气管周围淋巴细胞增生明显,浆细胞较多,有的可见生发中心。肺门淋巴结内滤泡增生,生发中心扩大,淋巴索内有多量的浆细胞,淋巴窦内网状细胞增生。 First, the SM ↑ shift test To normal rats (10) were injected sequentially intratracheally from the lungs of rats after 16, 33, 67, 90 and 130 days of dust stained SM ↑, after 2 months of anatomy . A large number of macrophages and macrophages macrophages in the interstitial part of lung tissue and alveolar cavity, between the fibroblasts and plasma cells proliferation, alveolar septum was significantly broadened. Bronchial lymphocyte proliferation was obvious, more plasma cells, some can be seen germinal center. Hilar lymph nodes within the follicular hyperplasia, germinal center expansion, there is a large number of lymphoid lymphocytes within the plasma cells, lymphoid sinus reticular cell proliferation.