为进一步了解头颈部肿瘤浸润、血管生长及淋巴结转移的生物学 ,该文综述作者多年来实验研究结果及相关文献报告。癌最基本的特性是向周围组织浸润以及局部和远处转移。从原位癌或浸润前期癌发展到浸润性癌的转化中 ,最主要的因素是其下基底膜的破坏。基底膜主要成分包括胶原蛋 In order to further understand the biology of head and neck tumor infiltration, blood vessel growth and lymph node metastasis, this article summarizes the experimental results and relevant literature reports of the authors for many years. The most basic features of cancer are infiltration into the surrounding tissues as well as local and distant metastases. From in situ carcinoma or infiltration of advanced cancer to invasive cancer transformation, the most important factor is the destruction of its basement membrane. The main components of the basement membrane include collagen