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目的:探讨术前多模态MRI序列中表观扩散系数(ADC)值对急性缺血性脑卒中(AIS)患者接受血管内治疗并成功再通后脑组织转归的预测能力。方法:选择郑州大学人民医院介入中心脑血管病科自2019年1月至12月行血管内治疗并成功再通的45例AIS患者，应用影像后处理软件对患者术前和术后1周内随访的MRI图像进行分析，测量并比较弥散加权成像(DWI)显示的脑梗死核心区、病变逆转区及脑梗死增加区术前ADC值的差异，应用受试者工作特征(ROC)曲线分析术前ADC值对患者DWI上病变逆转的预测能力。结果:所有患者血管成功再通后，均存在术前DWI上病变逆转区和脑梗死增加区。脑梗死核心区、病变逆转区及脑梗死增加区的术前ADC值依次增加，分别为0.555×10n -3(0.515×10n -3，0.608×10n -3) mmn 2/s、0.637×10n -3(0.600×10n -3，0.728×10n -3) mmn 2/s和0.948×10n -3(0.907×10n -3，0.950×10n -3) mmn 2/s，差异均有统计学意义(n P<0.05)。ROC分析显示术前ADC值预测患者DWI上病变逆转的准确度为87.1%(曲线下面积为0.871，n 95%CI：0.868~0.875，n P=0.000)，最佳ADC临界值为0.57×10n -3 mmn 2/s，其预测的敏感度为97.2%，特异度为68.3%。n 结论:AIS患者血管成功再通后不同转归脑组织的术前ADC值有明显差异，其可用于预测AIS患者脑组织的最终影像结局。“,”Objective:To explore the predictive ability of apparent diffusion coefficient (ADC) value in magnetic resonance imaging (MRI) mapping sequences in outcomes of brain tissues in patients with acute ischemic stroke (AIS) who had successful recanalization after endovascular treatment.Methods:A total of 45 patients with AIS who received endovascular treatment and successful recanalization in our hospital from January 2019 to December 2019 were selected. Post-processing software was used to analyze the images of these patients by MRI before surgery and one week after surgery, and the differences of ADC value in the core area of cerebral infarction, lesion reversal area and increased cerebral infarction area displayed by diffusion weighted imaging (DWI) before surgery were measured and compared. Receiver operating characteristic (ROC) curve was used to analyze the predictive ability of preoperative ADC value in the reversal of lesions showed by DWI.Results:Lesion reversal area and increased cerebral infarction area indicated by preoperative DWI existed in all patients after successful recanalization. The preoperative ADC values of the infarct core, lesion reversal area and increased cerebral infarction area were 0.555×10n -3 mmn 2/s (0.462, 0.648), 0.637×10n -3 mmn 2/s (0.509, 0.765) and 0.948×10n -3 mmn 2/s (0.905, 0.991), respectively, with significant differences (n P<0.05). The optimal cut-off point to predict DWI lesion reversal after successful recanalization was 0.57×10n -3mmn 2/s, and the accuracy was 87.1% (area under curve=0.871; n 95%CI: 0.868-0.875, n P=0.000), with sensitivity of 97.2% and specificity of 68.3%.n Conclusion:In patients with AIS after successful recanalization, the preoperative ADC values are obviously different in brain tissues with different outcomes, which can be used to predict the final imaging outcomes of the brain tissues.