羟丙基甲基纤维素（HPMC）和卡波姆（Carbol）等聚合物在亲水性骨架中用作凝胶形成刑，延缓药物释放。虽然HPMC本身不受PH变化影响，但药物释放速率受溶出介质的出影响。本文报道了用0．lino／L盐酸、PH4．5和PH7．5的磷酸盐缓冲液作溶出介质时，盐酸心得安在HPMC、K4M、卡波姆 Polymers such as HPMC and Carbol are used as gels in the hydrophilic matrix to delay the release of drugs. Although HPMC itself is not affected by pH changes, the rate of drug release is influenced by the dissolution medium. This article reports the use of 0. Lino / L hydrochloric acid, PH4.5 and PH7.5 phosphate buffer as a dissolution medium, hydrochloric acid experience in HPMC, K4M, carbomer