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目的：研究ｃ－ｍｙｃ蛋白在宫颈癌组织中的表达。方法：应用免疫组化ＳＰ法测定１５例正常宫颈上皮、１７例良性病变组织、５５例非典型增生、３例原位癌，１８例Ⅰ期、２９例Ⅱ期和４１例Ⅲ期宫颈浸润癌中ｃ－ｍｙｃ蛋白的表达，结合临床指标进行统计学分析。结果：正常宫颈上皮、良性宫颈病变、非典型增生，原位癌和Ⅰ期宫颈癌ｃ－ｍｙｃ蛋白高阳性率，Ⅱ期和Ⅲ期宫颈癌阳性率下降（Ｐ＜０．００５）。结论：ｃ－ｍｙｃ蛋白在高、中和低分化三组间无显著性差异（Ｐ＞０．０５）。
Objective: To study the expression of c-myc protein in cervical cancer. Methods: Immunohistochemical SP method was used to detect 15 cases of normal cervical epithelium, 17 cases of benign lesions, 55 cases of atypical hyperplasia, 3 cases of carcinoma in situ, 18 cases of stage Ⅰ, 29 cases of stage Ⅱ and 41 cases of stage Ⅲ cervical invasive carcinoma In c-myc protein expression, combined with clinical indicators for statistical analysis. Results: The positive rate of c-myc protein in normal cervical epithelium, benign cervical lesions, atypical hyperplasia, carcinoma in situ and stage Ⅰ cervical cancer and the positive rate of cervical cancer in stage Ⅱ and Ⅲ decreased (P <0.005). Conclusion: There is no significant difference in c-myc between high, medium and poorly differentiated three groups (P> 0.05).