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目的:对埃索美拉唑三联与奥美拉唑三联疗法治疗幽门螺杆菌(Hp)阳性十二指肠溃疡的临床效果进行探讨分析。方法:选取我院2014年3月至2016年12月接收的86例Hp阳性十二指肠溃疡患者为治疗对象,按照随机法将患者分为对照组和治疗组,43例对照组采用奥美拉唑、阿莫西林及克拉霉素进行治疗,43例治疗组患者采用埃索美拉唑、阿莫西林及克拉霉素进行治疗,对两组患者的治疗效果进行比较分析。结果:治疗组采用的埃索美拉唑、阿莫西林及克拉霉素治疗前临床症状缓解率与对照组相比较高(P<0.05),比较具有明显差异;治疗后两组患者临床症状缓解率比较无明显差异性(P>0.05)。结论:应用埃索美拉唑三联法治疗Hp阳性十二指肠溃疡具有很好的效果,安全有效,起效快,且药效持久,值得在临床上应用推广。
Objective: To investigate the clinical effects of esomeprazole triple therapy and omeprazole triple therapy on Helicobacter pylori (Hp) -positive duodenal ulcer. Methods: Totally 86 patients with Hp-positive duodenal ulcer received in our hospital from March 2014 to December 2016 were selected as the treatment subjects. According to the randomized method, the patients were divided into the control group and the treatment group. The control group of 43 patients The treatment of 43 patients in the treatment group was treated with esomeprazole, amoxicillin and clarithromycin. The therapeutic effects of the two groups of patients were compared. Results: The response rates of esomeprazole, amoxicillin and clarithromycin before treatment in treatment group were significantly higher than those in control group (P <0.05), and there was significant difference between the two groups after treatment No significant difference in the rate (P> 0.05). Conclusion: The triple therapy of esomeprazole for Hp-positive duodenal ulcer has a good effect, safe and effective, rapid onset, and long-lasting efficacy, it is worth to promote the clinical application.