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镉(Cd)是抗代谢物,其在肾或肝中异常的蓄积取决于进入的途径。将鱼放养在含有 CdSO_4 0.04ppm 的湖水中,一个月后与对照组相比,肝中镉高7倍,肾中镉高500倍。作者就镉是否干扰鱼肝脏储存 V_B_(12)的正常生理过程进行了实验。在实验室内以流动的湖水驯养意大利北方 Maggiore 湖的翻车鱼(Lepomis gibbosus L.),饲以专门配制的食物。实验组5条鱼在0.04 ppm Cd(硫酸盐)的湖水中预养2周后和对照组5条鱼一起饲以含~(58)Co 标记的V_B_(12)的食物,5小时后测定每条鱼的每克每分钟计数(cpm/g)。对照组为3,904±128(cpm/g),实验组为3,709±170(cpm/g),二组相差在10%之内。
Cadmium (Cd) is an anti-metabolite whose abnormal accumulation in the kidney or liver depends on the route of entry. The fish were stocked in a lake containing 0.04 ppm CdSO 4. One month later, cadmium in the liver was seven times higher and cadmium in the kidney 500 times higher. The authors conducted experiments on whether cadmium interferes with normal physiological processes in the storage of V_B_ (12) in fish liver. Sunfish (Lepomis gibbosus L.) is tamed in the laboratory in a flowing lake over Lake Maggiore in northern Italy and is fed exclusively prepared food. Five fish in the experimental group were pre-incubated for 2 weeks in 0.04 ppm Cd (sulfate) lake water and fed with 58 Co-labeled V_B 12 food together with 5 fish in the control group. After 5 hours, Fish per gram counts per minute (cpm / g). The control group was 3,904 ± 128 (cpm / g), the experimental group was 3,709 ± 170 (cpm / g), the difference between the two groups was within 10%.