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目的 :探讨单采血小板 (Plt)治疗急性白血病 (AL)出血的疗效。方法 :回顾性分析应用单采Plt治疗 96例各型AL出血患者的临床疗效 ,并与 5 8例使用一般止血药物行对症止血治疗的患者的疗效进行对照。结果 :治疗组单次输注Plt后 2 4h内Plt平均上升 16 2 3× 10 9/L ,输注前后Plt水平比较 ,差异有显著意义 ,对照组用药后Plt轻微下降。治疗组显效 71例 ,有效 16例 ,总有效率 91% ;对照组显效 3例 ,有效 14例 ,总有效率 2 9% ,两组间差异有显著意义。结论 :单采Plt输注能有效提高患者Plt水平 ,对AL出血的患者具有药物不可取代的止血效果 ,可明显降低AL患者致死性出血的发生率
Objective: To investigate the curative effect of apheresis (Plt) on acute leukemia (AL) hemorrhage. Methods: A retrospective analysis of the clinical efficacy of apathetic Plt therapy in 96 patients with AL-type hemorrhage was performed and compared with that of 58 patients treated with general hemostatic agents. Results: Plt increased by 16 2 3 × 10 9 / L within 24 hours after the single infusion of Plt in treatment group, and there was significant difference in Plt levels before and after infusion. Plt in control group decreased slightly. In the treatment group, 71 cases were markedly effective, 16 cases were effective, and the total effective rate was 91%. In the control group, 3 cases were markedly effective and 14 cases were effective. The total effective rate was 29%. There was significant difference between the two groups. CONCLUSIONS: PTSI Plt infusion can effectively improve the level of Plt in patients with AL bleeding with drugs irreplaceable hemostatic effect, can significantly reduce the incidence of AL patients with fatal bleeding