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本实验试图观察低剂量铅(Pb)染毒对妊娠中、晚期豚鼠母体及其胎鼠下丘脑促性腺激素释放激素(GnRH)和生长素释放抑制因子(SRIF)的含量以及妊娠母体血清孕酮水平的影响。本实验选用37只豚鼠,在其妊娠第22天开始经口给予醋酸铅水溶液。每日 Pb 剂量分别为0、5.5和11 mg/kg 体重,至第52天和第62天,将妊娠母鼠麻醉,剖腹并取出胎鼠。然后,分别测定母体和胎体血 Pb 含量,母体
This experiment attempted to observe the effect of low dose lead (Pb) exposure on the levels of hypothalamic gonadotropin-releasing hormone (GnRH) and ghrelin releasing factor (SRIF) and the serum levels of progesterone Horizontal impact. 37 guinea pigs were selected in this experiment, and oral administration of lead acetate solution was started on the 22nd day of gestation. Daily Pb doses were 0, 5.5 and 11 mg / kg body weight, respectively, and on Day 52 and Day 62, pregnant females were anesthetized and laparotomy was performed and fetuses were removed. Then, respectively, determination of maternal and carcass blood Pb content, maternal