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目的研究急性心肌梗死(AMI)经皮冠状动脉介入术(PCI)后早期静脉注射美托洛尔对患者预后的影响。方法将85例AMIPCI后的患者随机分为静脉注射美托洛尔组和口服美托洛尔组,观察发病后3个月内恶性心律失常、左室射血分数(LVEF)、心力衰竭(心衰)及死亡等并发症的差异。结果早期静脉注射美托洛尔可以使LVEF增加,需住院的心衰患者减少(P均<0.05),但恶性心律失常及死亡在2组间无明显差异。结论 AMIPCI后早期静脉注射美托洛尔可以改善预后。
Objective To investigate the effect of early intravenous metoprolol on patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI). Methods Eighty-five AMIPCI patients were randomly divided into metoprolol group and metoprolol group. The incidence of malignant arrhythmia, left ventricular ejection fraction (LVEF), heart failure Bad) and death and other complications. Results Early intravenous injection of metoprolol resulted in an increase in LVEF and a decrease in HF patients (P <0.05). However, there was no significant difference in malignant arrhythmia and death between the two groups. Conclusion The early intravenous injection of metoprolol after AMIPCI can improve the prognosis.