目的观察垂体后叶素联合酚妥拉明治疗上消化道出血的疗效及安全性。方法70例患者分成治疗组40例,应用垂体后叶素联合酚妥拉明治疗;对照组30例,应用施他宁治疗。结果两组疗效比较差异无统计学意义,治疗组肝性脑病发生率明显降低。结论垂体后叶素联合酚妥拉明治疗上消化道出血疗效好、安全、价廉。 Objective To observe the efficacy and safety of pituitrin combined with phentolamine in the treatment of upper gastrointestinal bleeding. Methods Seventy patients were divided into treatment group (n = 40), pituitrin combined with phentolamine (n = 30) and control group (n = 30). Results There was no significant difference in curative effect between the two groups, and the incidence of hepatic encephalopathy in the treatment group was significantly lower. Conclusion pituitrin combined with phentolamine treatment of upper gastrointestinal bleeding is good, safe and inexpensive.