血管扩张剂治疗急性肺水肿疗效已肯定。近研究证明氯丙嗪有阻断中枢及周围血管α—肾上腺受体的作用,并对动脉血管壁平滑肌有直接作用,能扩张强烈收缩的小动脉,因此具强有力的血管扩张效应。可用于治疗急性肺水肿。此外,应用较大量氯丙嗪可使患者处于一种“保护性抑制”状态,使器官的代谢及氧耗量明显降低,也有利于逆转急性肺水肿状态。近来,我们用氯丙嗪治疗二例顽固性急性肺水肿取得疗效,兹将结果报告如下: Vasodilator treatment of acute pulmonary edema effect has been affirmed. Recent studies have shown that chlorpromazine block central and peripheral vascular α-adrenergic receptor role, and the arterial wall smooth muscle has a direct effect, can expand the contraction of a small artery, and therefore has a strong vasodilation effect. Can be used to treat acute pulmonary edema. In addition, the use of larger amounts of chlorpromazine allows patients to be in a “protective” state of metabolism, and oxygen consumption of organs significantly reduced, but also help reverse the status of acute pulmonary edema. Recently, we used chlorpromazine in the treatment of two cases of intractable acute pulmonary edema to obtain the curative effect, hereby report the results as follows: