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由于假淋巴样白血病(PLL)形态特殊,很易造成误诊。该例因贫血住院,检查末梢血(PB)WBC计数正常。分类见90%的成熟小淋巴细胞,中性粒细胞颗粒少或有Pelger′s异常,可见巨大血小板,骨髓(BM)涂片及活检见40%的小淋巴细胞,红系和巨核数量减少。当时诊断为骨髓增生异常综合征。2个月后WBC升至50×10~9/L,BM及PB淋巴细胞达95%,且见10%的原淋细胞。由于苏丹黑、酸性磷酸酶阴性、非特异酯酶弱阳性而诊断为非典型淋巴细胞白血病,治疗4个月无效,WBC却升至140×10/L,因而作进一步检查。
Due to the special morphology of pseudolymphoid leukemia (PLL), it is easy to cause misdiagnosis. The case of hospitalization for anemia, check peripheral blood (PB) WBC count normal. Classification 90% of mature small lymphocytes, small number of neutrophils or Pelger’s abnormalities, visible large platelets, bone marrow (BM) smears and biopsies 40% of small lymphocytes, red and the number of megakaryocytes decreased. Was diagnosed with myelodysplastic syndrome. After 2 months WBC rose to 50 × 10 ~ 9 / L, BM and PB lymphocytes up to 95%, and see 10% of the original lymphocytes. As Sudan black, acid phosphatase-negative, non-specific esterase weak positive diagnosis of atypical lymphocytic leukemia, 4 months of treatment is invalid, WBC was raised to 140 × 10 / L, and thus further examination.