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目的 评价18F 脱氧葡萄糖 (FDG)PET肿瘤显像与99Tcm 亚甲基二膦酸盐 (MDP)全身骨显像对检出骨和远处转移的价值。方法 对 16例恶性肿瘤放化疗后的患者进行18F FDGPET显像和99Tcm MDP全身骨显像 ,并对两种结果进行了比较。结果 16例肿瘤患者中18F FDGPET显像皆阳性 ,其中 14例患者有远处转移 ,转移病灶共 62处 ,其中骨转移病灶 2 0处 ;在全身骨显像中 ,11例有局限性异常放射性浓聚 ,其中 2例为单一病灶 ,9例为多发病灶 ,共检出病灶 5 7处 ,另 5例骨显像正常。结论 18F FDGPET对恶性肿瘤的诊断具有较高的准确性和特异性 ,但对骨转移灶的诊断价值相对较差 ;99Tcm MDP显像阴性或单一病灶的可疑转移瘤患者有必要进行18F FDGPET检查 ,以明确诊断其他远处转移灶
Objective To evaluate the value of 18F deoxyglucose (FDG) PET tumor imaging and 99Tcm methylene diphosphonate (MDP) whole body scintigraphy in the detection of bone and distant metastasis. Methods 18F FDG PET and 99Tcm MDP whole body bone scintigraphy were performed on 16 patients with malignant tumor after radiotherapy and chemotherapy. The two results were compared. Results 18F FDG PETCT images were positive in all 16 tumor patients. Of 14 patients, there were 62 distant metastases and 62 metastatic lesions, including 20 bone metastatic lesions. In the whole body bone imaging, 11 patients had localized abnormal radioactivity Concentration, including two cases of a single lesion, nine cases of multiple lesions, a total of 57 lesions were detected, the other 5 cases of normal bone imaging. Conclusions 18F FDGPET has high accuracy and specificity for the diagnosis of malignant tumors, but it has poor diagnostic value for bone metastases. 18F FDG PETET is necessary for patients with suspected metastatic tumors with negative or single 99Tcm MDP imaging, To confirm the diagnosis of other distant metastases