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目的:探讨皮肤过敏原检测、血清总IgE水平测定在儿童哮喘中的临床意义。方法:选择2009年1月～2011年12月儿童哮喘患者178例为治疗组,选择同期无过敏性疾病、无呼吸系统疾病的健康儿童180例为对照组,应用皮肤点刺试验进行皮肤过敏原检测,应用ELISA法测定血清总IgE水平。结果:治疗组皮肤点刺试验过敏原阳性率为83.7%,对照组为18.3%,治疗组明显高于对照组(P<0.05)。治疗组血清总IgE显著高于对照组(P<0.05)。结论:血清总IgE水平测定为哮喘的临床诊治提供了有效依据,皮肤点刺试验检测皮肤过敏原适用于儿童患者,痛苦小,操作简单方便,避免对过敏原的接触对防治儿童哮喘有着重大的意义。
Objective: To investigate the clinical significance of skin allergen test and serum total IgE level in children with asthma. Methods: One hundred and eighty children with asthma were selected as the treatment group from January 2009 to December 2011. 180 healthy children without allergic diseases and no respiratory diseases were selected as the control group. The skin prick test The level of total serum IgE was measured by ELISA. Results: The skin prick test allergen positive rate was 83.7% in the treatment group and 18.3% in the control group, which was significantly higher in the treatment group than in the control group (P <0.05). Serum total IgE in treatment group was significantly higher than that in control group (P <0.05). Conclusion: The determination of serum total IgE level provides an effective basis for the clinical diagnosis and treatment of asthma. Skin prick test can detect skin allergens in children and patients. It is less painful and easy to operate. Avoid allergen exposure has a significant effect on the prevention and treatment of childhood asthma significance.