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目的探讨硫酸镁在妊高征治疗中的应用效果。方法选取2015年9月—2016年4月马山县中医医院诊治的妊高征患者70例,随机分为治疗组与对照组,各35例。对照组给予常规综合疗法,治疗组在对照组基础上加用硫酸镁静脉滴注联合肌肉注射治疗。比较两组患者治疗前后血压与蛋白尿变化、临床症状缓解时间及治疗满意度。结果治疗前两组患者舒张压、收缩压和蛋白尿水平比较,差异无统计学意义(P>0.05);治疗后治疗组患者舒张压、收缩压及蛋白尿水平低于对照组,临床症状(包括头晕、皮肤水肿、头痛)缓解时间短于对照组,治疗满意度高于对照组,差异有统计学意义(P<0.05)。结论硫酸镁在妊高征治疗中的应用效果肯定,可明显降低患者血压与蛋白尿水平,并早期缓解其临床症状,提升患者对于治疗效果的满意度,可作为妊高征首选用药方案。
Objective To investigate the effect of magnesium sulfate in the treatment of pregnancy induced hypertension. Methods Seventy patients with PIH diagnosed and treated in Mashan Hospital of TCM from September 2015 to April 2016 were randomly divided into treatment group and control group with 35 cases each. The control group was given conventional combination therapy. The treatment group was treated with intravenous infusion of magnesium sulfate and intramuscular injection on the basis of the control group. The changes of blood pressure and proteinuria, the clinical symptom relief time and the treatment satisfaction before and after treatment were compared between the two groups. Results There was no significant difference in diastolic blood pressure, systolic blood pressure and proteinuria between the two groups before treatment (P> 0.05). After treatment, the diastolic blood pressure, systolic blood pressure and proteinuria in the treatment group were lower than those in the control group. The clinical symptoms Including dizziness, skin edema, headache), the response time was shorter than that of the control group, the treatment satisfaction was higher than that of the control group, the difference was statistically significant (P <0.05). Conclusions The application of magnesium sulfate in the treatment of PIH is affirmative. It can significantly reduce the level of blood pressure and proteinuria, relieve its clinical symptoms early and improve the patient’s satisfaction with the therapeutic effect, which can be used as the first choice of medication for PIH.