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目的观察与比较绝经后骨质疏松治疗方法的近期疗效。方法选取该院在2015年1月—2016年1月接诊的绝经后骨质疏松患者279例,随机分成对照组、观察组和研究组,每组93例,对照组给予骨化三醇胶丸联合钙尔奇D3治疗;观察组在对照组治疗基础上增加鲑鱼降钙素治疗;研究组在对照组治疗基础上增加伊班膦酸钠治疗,比较3组患者1年后的骨密度、生活质量和疼痛的改善情况。结果对照组的3个指标均有改善,与基线比较差异无统计学意义(P>0.05);观察组的3个指标均有较大改善,与基线比较差异有统计学意义(P<0.05);研究组的3个指标均有显著改善,与基线比较差异有统计学意义(P<0.05)。结论钙剂和活性维生素D3的补充不能有效提高绝经后骨质疏松患者的骨密度;鲑鱼降钙素对患者有着良好的止痛作用,且对患者的骨密度以及生活质量有一定的改善作用:伊班膦酸钠对患者骨密度以及生活质量改善效果理想.且有较好的依从性。
Objective To observe and compare the short term efficacy of the treatment of postmenopausal osteoporosis. Methods A total of 279 patients with postmenopausal osteoporosis admitted from January 2015 to January 2016 in our hospital were randomly divided into control group, observation group and study group, with 93 cases in each group. The control group received calcitriol Pill combined with Calcium D3 treatment. The observation group was treated with salmon calcitonin on the basis of the control group. The study group was given ibandronate sodium on the basis of the control group. The bone mineral density, Improvements in quality of life and pain. Results The three indexes of the control group improved compared with the baseline (P> 0.05), and the three indexes of the observation group improved significantly compared with the baseline (P <0.05) The three indexes in the study group all improved significantly, with significant difference compared with the baseline (P <0.05). Conclusion Calcium supplementation with active vitamin D3 can not effectively increase the bone mineral density of postmenopausal osteoporosis patients. Salmon calcitonin has a good analgesic effect on patients with certain degree of improvement on the patient’s bone mineral density and quality of life: Baodin sodium for patients with bone mineral density and quality of life to improve the effect of the ideal and has good compliance.