论文部分内容阅读
慢性肝脏疾病病人常发生血小板减少和免疫学异常。为调查慢性肝脏病人免疫学异常和血小板减少间的内部作用。作者对慢性肝脏病人的血小板计数、血清IgG、血小板相关IgG(PAIgG)和IgG 免疫复合物进行了前瞻性的对照研究。慢活肝(CAH)27例。原发性胆汁性肝硬化(PBC)38例,酒精性肝脏疾病(ALD)27例,自身免疫性血小板减少症11例。13例健康者作对照。所有对象均取血检测血小板计数、血清IgG、PAIgG 和IgG 免疫复合物。结果:肝脏疾病组病人血清IgG 平均浓度增加,ITP 和对照组间无明显差异。各类肝脏病人的PAIgG 升高,ITP 组PAIgG 值最高。13例对照组中1例的IgG 免疫复合物>500mg/L,ITP 组11例中3
Chronic liver disease patients often occur thrombocytopenia and immunological abnormalities. To investigate the internal role of immunological abnormalities and thrombocytopenia in patients with chronic liver disease. The authors conducted a prospective, controlled study of platelet counts, serum IgG, platelet-associated IgG (PAIgG), and IgG immune complexes in patients with chronic liver disease. Slow living liver (CAH) in 27 cases. 38 cases of primary biliary cirrhosis (PBC), 27 cases of alcoholic liver disease (ALD), and 11 cases of autoimmune thrombocytopenia. Thirteen healthy controls. All subjects received blood for platelet count, serum IgG, PAIgG and IgG immune complexes. Results: The average serum IgG level in patients with liver disease increased, but there was no significant difference between ITP and control group. PAIgG increased in all kinds of liver patients, PAIgG value in ITP group was the highest. One of 13 patients in the control group had an IgG immune complex of> 500 mg / L and 11 patients in the ITP group