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对３４例妊高征孕妇、３０例健康未妊娠妇女及３５例正常孕妇的血脂代谢进行了检测，分别测定了胆固醇（ＴＣ）、甘油三酯（ＴＧ）、低密度脂蛋白－胆固醇（ＬＤＬ－Ｃ）和高密度脂蛋白－胆固醇（ＨＤＬ－Ｃ），并计算ＬＤＬ－Ｃ／ＨＤＬ－Ｃ比值及动脉粥样硬化指数（ＡＩ）。结果：正常妊娠中期血脂水平与非孕妇血脂水平差异无显著性（Ｐ＞０．０５），妊娠晚期与非孕妇血脂水平及妊高征轻、中度与妊娠晚期血脂水平比较，差异均无显著性，Ｐ均＞０．０５，但重度妊高征ＴＧ和ＡＩ明显增高，其平均值加一个标准差＞３小于４。血脂水平与急性动脉粥样硬化及胎婴儿预后无明显相关。提示：（１）高脂血症分Ⅳ型，重度妊高征属Ⅳ型高脂血症。（２）妊娠期脂质代谢为妊娠晚期有大量胎肪积留，妊娠晚期血脂水平高于妊娠中期，可能为正常生理变化或与易发妊高征有关。（３）妊高征脂质代谢为重度妊高征ＴＧ和Ａｌ水平明显增高，胎盘血管粥祥硬化与ＴＧ增高导致脂质过氧化物增多或与免疫反应有关，其原因不明可能是多种因素的作用。
The blood lipid metabolism of 34 pregnant women with PIH, 30 healthy pregnant women and 35 normal pregnant women were measured. The levels of TC, TG, LDL- C) and high-density lipoprotein-cholesterol (HDL-C) were calculated and LDL-C / HDL-C ratio and atherosclerosis index (AI) were calculated. Results: There was no significant difference in serum lipids between normal pregnant women and non-pregnant women (P> 0.05). There was no significant difference in serum lipid level between late pregnancy and non-pregnant women, mild to moderate pregnancy-induced hypertension, moderate to late pregnancy Sex, P> 0.05, but severe PIH TG and AI were significantly increased, the average plus a standard deviation> 3 less than 4. Serum lipid levels were not significantly associated with acute atherosclerosis and fetal infant outcomes. Tip: (1) hyperlipidemia sub-type Ⅳ, severe pregnancy-induced hypertension type Ⅳ hyperlipidemia. (2) The lipid metabolism in pregnancy is a large number of late pregnancy accumulation of fetal fat, high blood lipid levels in late pregnancy than in the second trimester, may be normal physiological changes or prone to pregnancy-induced hypertension. (3) PIH lipid metabolism is significantly elevated levels of TG and Al in severe PIH. Placental atherosclerosis and TG increased lead to increased lipid peroxidation or immune response, the unknown reasons may be a variety of factors Role.