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目的:探讨中药辅助治疗肾结石体外震波碎石术后的疗效及对患者血肌酐(SCr)及尿素氮(BUN)水平的影响。方法:选择本院收治的158例肾结石患者,将其随机分为观察组80例、对照组78例,对照组患者仅采取体外震波碎石术治疗,观察组患者术后联合中药辅助治疗,比较2组患者临床疗效、碎石次数、结石排净时间以及患者血SCr、BUN变化情况。结果:观察组治疗后总有效率为92.50%(74/80)、对照组患者治疗后总有效率为78.21%(61/78),经比较,观察组患者治疗总有效率显著高于对照组(P<0.05)。2组排石次数情况比较,观察组显著优于对照组,差异有统计学意义(P<0.05)。观察组结石排净时间(5.18±1.46)天,对照组(9.06±2.25)天,2组比较,差异均有统计学意义(P<0.05)。2组患者术前SCr、BUN水平比较,差异无统计学意义(P>0.05);术后3天2组患者SCr、BUN均较术前显著升高(P<0.05),而2组间比较,差异无统计学意义(P>0.05);术后7天2组患者SCr、BUN均较术前显著升高(P<0.05),且对照组显著高于观察组(P<0.05);术后14天,观察组SCr、BUN与治疗前比较,差异无统计学意义(P>0.05),而对照组SCr、BUN均显著高于治疗前(P<0.05),2组间比较差异有统计学意义(P<0.05)。结论:中药辅助体外震波碎石术治疗肾结石能够显著提高临床疗效,缩短排石时间、减少碎石次数、且有助于术后肾功能的恢复,值得临床推广运用。
Objective: To investigate the curative effect of traditional Chinese medicine adjuvant therapy on extracorporeal shock wave lithotripsy of kidney stones and its effect on serum creatinine (SCr) and blood urea nitrogen (BUN). Methods: A total of 158 patients with nephrolithiasis were selected and randomly divided into observation group (n = 80) and control group (n = 78). Patients in the control group were treated with extracorporeal shock wave lithotripsy only. Patients in the observation group received adjuvant therapy with traditional Chinese medicine The clinical curative effect, the number of gravel, the time of stone discharge and the changes of SCr and BUN in blood were compared between the two groups. Results: The total effective rate was 92.50% (74/80) in the observation group and 78.21% (61/78) in the control group after treatment. The total effective rate in the observation group was significantly higher than that in the control group (P <0.05). Compared with the control group, the observation group was significantly better than the control group (P <0.05). The stones in the observation group had a net discharge time (5.18 ± 1.46) days and the control group (9.06 ± 2.25 days), and the differences were statistically significant (P <0.05). There was no significant difference in preoperative SCr and BUN levels between the two groups (P> 0.05). The levels of SCr and BUN in the two groups were significantly higher than those before operation (P <0.05) (P> 0.05). The levels of SCr and BUN in the two groups at 7 days after operation were significantly higher than those before operation (P <0.05), and were significantly higher in the control group than those in the observation group (P <0.05). There was no significant difference between the two groups After 14 days, there was no significant difference in SCr, BUN between observation group and before treatment (P> 0.05), while SCr and BUN in control group were significantly higher than those before treatment (P <0.05) Significance (P <0.05). Conclusion: The Chinese medicine-assisted extracorporeal shock wave lithotripsy can significantly improve the clinical efficacy, shorten the row time, reduce the number of gravel, and contribute to the recovery of postoperative renal function, worthy of clinical promotion and application.