进行性核上性麻痹(Progressive sup-ranuclear palsy P S P)是一种相当少见的异质性系统变性病。现将我们收治1例报告如下。黄××、女、60岁,1983年11月始有行走徐缓,不自主发笑,当地精神病院诊断为“脑动脉硬化。”1984年秋步态艰难,步甚宽,需人扶送入厕。静止时右手出现震颤,持续数月后消失。1985年5月双眼下视不能,继之上视及左右侧视困难、仅能往前平视。同年9月双腿僵硬发直、始动困难,一旦起步,小碎步前冲后又往往向后跌倒。从一侧转到另一侧躯干活动非常困难。同年底坐也不稳,乃至卧床不起,翻身及卧位坐起均 Progressive sup-ranuclear palsy P S P is a relatively rare heterogeneous systemic degenerative disease. Now we receive a report as follows. Huang × ×, female, 60 years old, beginning in November 1983 began walking slowly, involuntarily amused, the local mental hospital diagnosed as “cerebral arteriosclerosis.” 1984 autumn difficult gait, very wide steps, people need to help the toilet. Resting his right hand tremor, lasted several months later disappeared. May 1985 binocular vision can not, followed by the top and left and right side of the visual difficulties, only forward head-up. The same year in September stiff legs straight, difficult to start, once started, small broken step forward and often fall backward. Going from one side to the other is extremely difficult. At the end of the same year sitting is not stable, and even bedridden, stand up and sit up