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最近,我们从有机溶媒提取后的石花中提取出一种粗多糖,为浅褐色粉末状固体,对小鼠的LD_(50)为480±17.9mg/kg,其抗辐射活性比3,5-二羟基甲苯还高。 实验用昆明种小鼠420只,经900拉德~(60)Coγ线一次全身照射,动物在照前15分和1、2、4、8、12、18和24小时分别腹腔注射石花粗多糖水溶液150mg/kg,每组20～40鼠,均设同数量鼠对照,比较其照后30天的存活率。结果表明:除照前4小时给药两组差异不明显外,其他7个时相给药组小鼠存活率都明显高于对照组。提高存活率22.5～55％。此外,它
Recently, we extracted a crude polysaccharide from the stone flower after organic solvent extraction as a light brown powdery solid with an LD_ (50) of 480 ± 17.9 mg / kg against mice, showing a higher anti-radiation activity than 3,5- Dihydroxy toluene is also high. A total of 420 Kunming mice were subjected to a total body irradiation of 900 rad (60) Co γ ray. Animals were intraperitoneally injected with the crude polysaccharides of Lithocarpus at 15 and 1, 2, 4, 8, 12, 18 and 24 hours Aqueous solution 150mg / kg, each group of 20 to 40 mice, were set the same number of rats control, compared to 30 days after the survival rate. The results showed that the survival rates of mice in the other seven phases of administration were significantly higher than those in the control group, except that the difference between the two groups was not obvious 4 hours before irradiation. Raise the survival rate of 22.5 ~ 55%. In addition, it