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目的探讨妊娠期糖尿病合并高血压患者自主神经功能与心率变异性(HRV)的关系。方法选取108例博爱县人民医院产检孕妇,根据葡萄糖耐量试验结果分为妊娠期高血压糖耐量正常组(A组)56例和2型糖尿病组(B组)52例,均在孕中期行动态心电图检查,对两组患者心率变异性时域指标和心率指标进行回顾性分析。结果 B组心率变异性时域指标值较A组均减小,差异有统计学意义(P<0.05);B组平均心率、心率动态变化、最慢心率较A组均增高,差异有统计学意义(P<0.05)。结论妊娠期高血压合并糖尿病患者HRV明显降低,妊娠期高血压患者心率昼夜节律已受损,妊娠期高血压合并糖尿病患者心率昼夜节律受损情况进一步加重,心脏自主神经功能失调。
Objective To investigate the relationship between autonomic nervous function and heart rate variability (HRV) in patients with gestational diabetes mellitus and hypertension. Methods A total of 108 pregnant women of Bo’ai County People’s Hospital were selected and divided into 56 cases of normal glucose tolerance group (group A) and 52 cases of type 2 diabetes group (group B) according to the results of glucose tolerance test. ECG examination, heart rate variability of the two groups of time-domain and heart rate indicators were retrospectively analyzed. Results The time-domain index of heart rate variability in group B was lower than that in group A (P <0.05). The average heart rate, the dynamic change of heart rate and the slowest heart rate in group B were significantly higher than those in group A Significance (P <0.05). Conclusion The HRV of patients with hypertensive disorder complicated with diabetes mellitus during pregnancy is significantly lower. The circadian rhythm of heart rate in patients with gestational hypertension is impaired. The circadian rhythm of heart rate in hypertensive patients with gestational hypertension aggravates further. Autonomic dysfunction of the heart.