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现代免疫学已涉及基础和临床医学的各个领域。过去仅作为特异性预防结核病的卡介苗(BCG)现在临床上还可用于非特异性免疫疗法。 临床应用 一、抗肿瘤作用 BCG通过T细胞的致敏并产生相关因子,提高巨噬细胞代谢、吞噬功能和杀肿瘤能力;抑制药物代谢酶(如去甲基酶、羟化酶),延长抗肿瘤药物的作用,防止或扭转X射线、激素、抗淋巴血清引起的免疫功能下降状态,减轻抗肿瘤药物的免疫抑制作用,从而延长肿瘤病人的缓解期和生存期。
Modern immunology has involved various fields of basic and clinical medicine. Past BCG (BCG), which was specifically designed to prevent tuberculosis, is now also clinically used for non-specific immunotherapy. Clinical application 1. Anti-tumor effect BCG sensitizes and produces related factors through T cells, improves macrophage metabolism, phagocytosis and tumor-killing ability; inhibits drug-metabolizing enzymes (such as demethylase, hydroxylase) and prolongs resistance The role of oncological drugs to prevent or reverse X-rays, hormones, anti-lymphocyte serum-induced decline in immune function, reduce the immunosuppressive effects of anti-tumor drugs, thereby prolonging the remission and survival of cancer patients.