许多药物与地高辛联用使血清地高辛浓度(SDC)升高,引起洋地黄中毒者屡有所见,但莫雷西嗪(moricizine,乙吗噻嗪)引起洋地黄中毒国内尚未见报道.现将我们所遇1例报道如下.患者男,57岁.因患高血压5年,活动后心悸、气喘2月,加重并不能平卧3天入院.体检:BP 22/14kPa,P 95次/分,脉律不齐,有缺脉,双肺底可闻及湿啰音,心界向左下扩大,心尖区Ⅲ级收缩期吹风样杂音,HR 112次/分,心律绝对不规则.肝肋下2cm,肝颈返流征阳性,双下肢凹陷性水肿.心电图示:快速性心房颤动.血清电解质、尿素氮及肌酐均在正常范围.入院后,即刻给予西地兰0.4mg稀释后静脉注射,口服依那普利10mg/日,地高辛0.25mg/日,丁尿胺lmg/日,门冬氨酸钾镁6片/日(分3次).1周 Many drugs combined with digoxin to make serum digoxin concentration (SDC) increased, often caused by digitalis poisoning are seen, but no intra-digitalis methicillin (moricizine, ethylthiazide) has been seen Reported that we encounter a case reported as follows.Patients male, 57 years old .Hypertensive for 5 years, after the event of palpitations, asthma in February, aggravating and can not be supine for 3 days admitted to hospital Physical examination: BP 22 / 14kPa, P 95 beats / min, irregular pulse, lack of pulse, the end of both lungs can be heard and wet aureus, left heart to expand the heart, apical Ⅲ grade systolic hair-like murmur, HR 112 beats / min, absolute irregular heartbeat .Liver ribs 2cm, liver reflux syndrome was positive, both lower extremity edema.Electrocardiogram: rapid atrial fibrillation.Electrolyte, urea nitrogen and creatinine were in the normal range.After admission, cedilanid 0.4mg diluted After intravenous, oral enalapril 10mg / day, digoxin 0.25mg / day, butanil lmg / day, potassium aspartate 6 / day (divided 3 times.) 1 week