本文探讨了制取赖氨匹林的工艺。使L-赖氨酸和DL-赖氨酸分别同阿斯匹林的乙醇溶液反应后,再加入过量的丙酮,从而析出赖氨匹林。L-赖氨酸反应液析出的结晶不完整,且滤取干燥后吸水性大,制备困难。而DL-赖氨酸反应液中析出的结晶完整,吸水性小,收率多。经多次试制结果表明收率达90％以上,符合质量标准。 This article explores the process of preparing acetaminophen. L-lysine and DL-lysine were respectively reacted with aspirin in ethanol, and then an excess of acetone was added to precipitate lysicillin. L-lysine reaction solution crystallization is incomplete, and after filtration and drying water absorption, preparation difficult. However, the crystals precipitated in the DL-lysine reaction solution are intact, the water absorption is small, and the yield is high. After several trial results show that the yield of 90% or more, in line with quality standards.