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壳聚糖是自然界中唯一存在的碱性多糖,具有生物可降解性、生物相容性、安全性和抗菌性等优良性能,由于壳聚糖所具有的抗菌性能,其在伤口缝合、处理植物种子、消毒剂、洗手液等方面获得了广泛的应用。季铵盐型壳聚糖衍生物材料是提高壳聚糖抗菌性的重要方向之一,也是抗菌材料研究的热点领域。本文综述了国内外有关壳聚糖季铵盐的不同制备方法,总结了影响壳聚糖季铵盐抗菌性的各种因素,并展望了季铵盐型壳聚糖抗菌剂今后的发展方向。
Chitosan is the only alkaline polysaccharide in nature. It has excellent properties such as biodegradability, biocompatibility, safety and antibacterial properties. Due to the antibacterial property of chitosan, chitosan sutured in wounds and treated plants Seeds, disinfectants, hand sanitizer, etc. has been widely used. Quaternary ammonium salt type chitosan derivative material is to improve the antimicrobial properties of chitosan one of the important directions, but also the hot area of antibacterial materials research. This article reviews the different preparation methods of chitosan quaternary ammonium salt at home and abroad, summarizes various factors that affect the antibacterial activity of chitosan quaternary ammonium salt, and prospects the future development of quaternary ammonium salt chitosan antibacterial agent.