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[Objective] To compare effects of different polar parts of Galium aparine L.extracts on anti-leukemia activity.[Method] Galium aparine L.was refluxed with 95% ethanol and the obtained extracts were separated into different polar parts by Soxhlet extractor.The relationship between polar parts and biological activity was investigated through leukemia cells-K562 in vitro antitumor activity test.[Result] The content of extractum was the highest in normal butanol part,followed by dichloromethane part.The extractum and polar parts had a certain inhibitory activity on the growth of K562 cells,in which the latter was better than the former.Ether,dichloromethane and ethyl acetate polarity components had the stronger inhibitory activity,while normal butanol phase’s inhibition was weak.[Conclusion] Extracts of Galium aparine L.contained some anti-cancer components that could be used in developing new anticancer drugs.
[Objective] To compare effects of different polar parts of Galium aparine L. extracts on anti-leukemia activity. [Method] Galium aparine L.was refluxed with 95% ethanol and the obtained extracts were separated into different polar parts by Soxhlet extractor. relationship between polar parts and biological activity was investigated through leukemia cells-K562 in vitro antitumor activity test. [Result] The content of extractum was the highest in normal butanol part, followed by dichloromethane part. The extractum and polar parts had a certain inhibitory activity on the growth of K562 cells, in which the latter was better than the former. Ether, dichloromethane and ethyl acetate polarity components had the stronger inhibitory activity, while normal butanol phase’s inhibition was weak. [Conclusion] Extracts of Galium aparine L.contained some anti-cancer components that could be used in developing new anticancer drugs.