1病例报告患者女,50岁。剧烈干咳2个月。在外院就诊,先后被诊断为“上呼吸道感染”“急性气管-支气管炎”等,给予抗感染及止咳化痰等药物治疗,效果欠佳,且咳嗽症状逐渐加重,以夜间为甚。追问病史,本次发病时无发热、咽痛、流涕等感冒症状,既往无慢性呼吸道病史;约10周前被诊断 1 case report Patients female, 50 years old. Severe cough 2 months. In the outpatient hospital, has been diagnosed as “upper respiratory tract infection” “acute tracheo-bronchitis” and so on, given anti-infective and cough and phlegm and other drug treatment, the effect is poor, and the symptoms of cough gradually aggravate, even at night. Asked history, the incidence of fever, sore throat, runny nose and other cold symptoms, no previous history of chronic respiratory disease; about 10 weeks ago was diagnosed