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大肠癌病人初次手术时约10％～25％有肝脏转移。不经治疗,中位生存期只有4～7个月。近年来,随着手术、化疗、栓塞治疗及其它疗法的进展,预后已见明显改善。本文就大肠癌肝转移的治疗近况作一综述。1 手术治疗 手术切除是目前治疗大肠癌肝转移唯一有可能治愈的手段,经手术治疗后,病人的5年生存率达20％～45％。公认的手术适应证是:①原发肿瘤已得到根治或控制,无肝外肿瘤存在;②转移灶局限在肝内,为单发或多发而局限于一叶内;③肝功能正常。手术方式取决于转移灶,局限于一叶或半肝,可行肝叶或半肝
About 10% to 25% of patients with colorectal cancer have liver metastases during the initial operation. Untreated, the median survival was only 4 to 7 months. In recent years, with the advancement of surgery, chemotherapy, embolization therapy, and other therapies, the prognosis has improved significantly. This article reviews the current status of treatment of liver metastases in colorectal cancer. 1 Surgical treatment Surgical resection is currently the only possible cure for liver metastases of colorectal cancer. After surgical treatment, the 5-year survival rate of patients is 20% to 45%. The accepted surgical indications are: 1 primary tumor has been cured or controlled, there is no extrahepatic tumor; 2 metastases confined to the liver, single or multiple and limited to a leaf; 3 liver function is normal. The surgical method depends on the metastasis, limited to a leaf or hemi liver, viable liver or hemi liver