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本文观测了冷习服大鼠及其冻伤后血管内皮细胞（ＶＥＣ）的某些功能的变化。结果表明，与未习服组比，冷习服鼠循环血中ＶＥＣ计数显著增加，血中６－ｋｅｔｏ－ＰＧＦ１α和ＴＸＢ２含量明显升高，而Ｔ／Ｐ比值接近，血清血管紧张素Ⅰ转换酶（ＡＣＥ）活性减低。冻伤后未习服组这些指标除ＡＣＥ显著降低外，其余均急剧升高；而冷习服组仅见短暂轻微的改变或改变不明显，且其冻足组织活存面积亦显著增加。表明冷习服后，ＶＥＣ发生了代谢更新率加快、功能增强的适应性改变，有利于提高机体对寒冷损伤的应激和修复能力
This article observed changes in some functions of cold acclimated rats and their post-frost vascular endothelial cells (VECs). The results showed that compared with the non-served group, the VEC counts in circulating blood increased significantly in cold-acclimated rats, and the levels of 6-keto-PGF1α and TXB2 were significantly increased, while the T / P ratios were close. Serum angiotensin Ⅰ converting enzyme (ACE) activity decreased. In addition to the ACE decreased significantly in the group not treated with frostbite, the other indexes increased sharply. However, the cold acclimation group showed only a slight transient change or insignificant change, and the survival area of the frozen foot tissue also increased significantly. After cold acclimation, VEC had a metabolic update rate to speed up, enhance the adaptive changes, help to improve the body’s ability to cold damage and repair capacity