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血栓闭塞性脉管炎是一种主要侵害人体中小动、静脉的慢性阻塞性周围血管病,心脑肺肾肠等器官也可发病,但以四肢中下肢发病最为常见。常受累的血管有下肢胭动脉、胫前动脉、胫后动脉,上肢尺动脉、桡动脉及与以上血管伴行的各静脉血管。初期病变为血管内膜发炎肿胀,管腔狭窄,血流减少,组织营养障碍。后期病变为血管变硬、增生、纤维化,血栓形成,导致血管闭塞。
Thromboangiitis obliterans is a chronic obstructive peripheral vascular disease that mainly affects small, medium and small veins of the human body. Heart, brain, lung, kidney, kidney and other organs can also occur. Often involved in the lower extremities of cilia, anterior tibial artery, posterior tibial artery, upper limb ulnar artery, radial artery and the vein associated with the above vessels. Initial lesions of the intima of the swollen blood vessels, stenosis, blood flow, tissue disorders. Late lesions as hardening of the blood vessels, hyperplasia, fibrosis, thrombosis, leading to vascular occlusion.