论文部分内容阅读
目的:探讨双氯芬酸在临床使用中所致不良反应的一般规律及特点,为临床合理用药提供参考。方法:对1994年1月～2008年2月国内公开发表的医、药杂志刊登的有关双氯芬酸所致不良反应进行分类统计与分析。结果:双氯芬酸所致不良反应有73例,临床表现包括消化道出血、变态反应、过敏性休克、急性肾功能衰竭等,累及消化系统、泌尿系统、血液系统、皮肤及其附件等。结论:应重视双氯芬酸发生的不良反应,以确保用药安全。
Objective: To investigate the general rules and characteristics of adverse reactions caused by diclofenac in clinical use, and to provide reference for clinical rational use of drugs. Methods: The classification and statistics of adverse reactions caused by diclofenac published in the domestic published medical and pharmaceutical journals from January 1994 to February 2008 were classified and analyzed. Results: There were 73 cases of adverse reactions caused by diclofenac. The clinical manifestations included gastrointestinal bleeding, allergic shock, anaphylactic shock and acute renal failure, which involved the digestive system, urinary system, blood system, skin and its accessories. Conclusion: Diclofenac should pay attention to the adverse reactions to ensure the safety of medication.