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生命科学是关乎人类健康的重要研究领域.基于无机纳米材料为载体的生物无机材料推动了生命科学的发展.水滑石(LDHs)作为一种二维无机纳米材料,具有层板金属离子种类和比例可调控以及层间可插层的特性,近年来在生物医学领域受到广泛关注.本文重点介绍了水滑石纳米复合材料的物理化学结构、作为基因/药物载体的应用,以及在新型诊疗一体化复合材料领域的应用和优势.此外,通过细胞和活体实验,进一步探讨了水滑石纳米复合材料的细胞输运机制、诊断成像以及肿瘤治疗效果,并展望了水滑石纳米复合材料在生物医学领域的发展前景.
Life science is an important research field about human health.Life bio-inorganic materials based on inorganic nanomaterials promote the development of life science.Hydrolithosiloxane (LDHs) as a two-dimensional inorganic nanomaterials, with the type and proportion of metal ions Tunable and interlamellar intercalation properties have received widespread attention in the biomedical field in recent years.This paper focuses on the physicochemical structure of hydrotalcite nanocomposites as a gene / drug carrier application, as well as in the new integrated diagnosis and treatment of treatment In addition, the cell transport mechanism, diagnostic imaging and tumor therapeutic effect of hydrotalcite nanocomposites were further discussed by cell and in vivo experiments, and the development of biomedical materials in hydrotalcite nanocomposites prospect.