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四川为我国黄连素(小蘖碱)主要产地之一。一九五八年起,在盆地及边缘地区,部分富有黄连素植物资源的专、县,先后发展了农村社、队的黄连素副业生产。就地采集原料,使用简易设备,以水和食盐制取粗制盐酸黄连素。粗制品转运城市院厂精制,做成药用盐酸黄连素及盐酸黄连素制剂。最高年产量达20余吨。近年,药用黄连素及其制剂产量急剧下降,严重脱销,究其原因主要是:①省内黄连素资源不清,一个地区开始生产三至五年后,资源基本用完,农村副业生产黄连素无法就地进行。②现用黄连素简易生产工艺,产率低,质量差,甚至由于某些原料品种中
Sichuan is one of the main producing areas of berberine (berberine) in China. Since 1958, in the basin and the marginal areas, some counties and counties rich in berberine plant resources have successively developed the production of berberine in rural communities and teams. Collect raw materials on site, use simple equipment, and prepare crude berberine hydrochloride with water and salt. The crude product was transported to the city hospital for refinement and made medicinal berberine hydrochloride and berberine hydrochloride preparations. The highest annual output of more than 20 tons. In recent years, the production of medicinal berberine and its preparations has declined sharply and has been severely out of stock. The main reasons are: 1 The resources of berberine in the province are unclear. After three to five years from the start of production in one area, the resources are basically used up, and the rural side produces Coptis Can not be carried out on the spot. 2 is a simple production process of berberine, low yield, poor quality, even due to some raw materials