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目的分析紫杉醇注射液致过敏性休克的发生特点及相关因素,为临床合理使用提供参考。方法利用中国医院数字图书馆CHKD期刊全文库检索1994-2009年的中文期刊,对检索到的34例紫杉醇注射液致过敏性休克病例进行回顾性分析。结果紫杉醇注射液可致过敏性休克,严重的过敏性休克可致患者死亡。结论严格用药指征,加强药品不良反应监测,促进临床合理用药,严防死亡病例发生。
Objective To analyze the occurrence and related factors of anaphylactic shock induced by paclitaxel injection and provide reference for clinical rational use. Methods The Chinese Journal of Hospital Library digital library CHKD periodicals were searched in Chinese periodicals from 1994 to 2009. The retrieved 34 cases of paclitaxel-induced allergic shock were retrospectively analyzed. Results paclitaxel injection can cause anaphylactic shock, severe anaphylactic shock can cause death in patients. Conclusion Strict indications for medication, drug adverse reaction monitoring to promote and promote rational drug use, prevent deaths.